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Laboratorio de Biología Estructural y Molecular (BEM)

Centro de Equipamiento Mayor (CEM)

Facultad de Ciencias

Universidad de Chile

Las Palmeras 3425

Ñuñoa, Santiago

Chile

cem@uchile.cl

+56 2 29787380

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Publicaciones Díaz-Espinoza R. (últimos diez años)

Prion-like characteristics of the bacterial protein microcin E492.

March 31, 2017

Shahnawaz M, Park KW, Mukherjee A, Diaz-Espinoza R, Soto C.
Sci Rep. 2017 Mar 31;7:45720. doi: 10.1038/srep45720.

Molecular interaction between type 2 diabetes and Alzheimer's disease through cross-seeding of protein misfolding.

January 3, 2017

Moreno-Gonzalez I, Edwards Iii G, Salvadores N, Shahnawaz M, Diaz-Espinoza R, Soto C.
Mol Psychiatry. 2017 Jan 3. doi: 10.1038/mp.2016.230.

Strain-dependent profile of misfolded prion protein aggregates.

February 15, 2016

Morales R, Hu PP, Duran-Aniotz C, Moda F, Diaz-Espinoza R, Chen B, Bravo-Alegria J, Makarava N, Baskakov IV, Soto C.
Sci Rep. 2016 Feb 15;6:20526. doi: 10.1038/srep20526

The extent of protease resistance of misfolded prion protein is highly dependent on the salt concentration.

January 31, 2014

Concha-Marambio L, Diaz-Espinoza R, Soto C.
J Biol Chem. 2014 Jan 31;289(5):3073-9. doi: 10.1074/jbc.M113.513267.

Protein misfolding cyclic amplification of infectious prions.

June 28, 2012

Morales R, Duran-Aniotz C, Diaz-Espinoza R, Camacho MV, Soto C.
Nat Protoc. 2012 Jun 28;7(7):1397-409. doi: 10.1038/nprot.2012.067.

High-resolution structure of infectious prion protein: the final frontier.

April, 2012

Diaz-Espinoza R, Soto C.
Nat Struct Mol Biol. 2012 Apr 4;19(4):370-7. doi: 10.1038/nsmb.2266.

Kosmotropic anions promote conversion of recombinant prion protein into a PrPSc-like misfolded form.

February 9, 2012

Diaz-Espinoza R, Mukherjee A, Soto C.
PLoS One. 2012;7(2):e31678. doi: 10.1371/journal.pone.0031678.

Generation of prions in vitro and the protein-only hypothesis.

April, 2010

Diaz-Espinoza R, Soto C.
Prion. 2010 Apr-Jun;4(2):53-9.

Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases.

March 31, 2010

Morales R, Estrada LD, Diaz-Espinoza R, Morales-Scheihing D, Jara MC, Castilla J, Soto C.
J Neurosci. 2010 Mar 31;30(13):4528-35. doi: 10.1523/JNEUROSCI.5924-09.2010

Transport of prion protein across the blood-brain barrier.

July 5, 2009

Banks WA, Robinson SM, Diaz-Espinoza R, Urayama A, Soto C.
Exp Neurol. 2009 Jul;218(1):162-7. doi: 10.1016/j.expneurol.2009.04.025.

Domain folding and flexibility of Escherichia coli FtsZ determined by tryptophan site-directed mutagenesis.

August, 2007

Díaz-Espinoza R, Garcés AP, Arbildua JJ, Montecinos F, Brunet JE, Lagos R, Monasterio O.
Protein Sci. 2007 Aug;16(8):1543-56.

Overcoming electrostatic repulsions during amyloid assembly: effect of pH and interaction with divalent metals using model peptides.

March 10, 2017

Diaz-Espinoza R, Nova E, Monasterio O.

Arch Biochem Biophys. 2017 Mar 10;621:46-53. doi: 10.1016/j.abb.2017.03.003

Development of a novel catalytic amyloid displaying a metal-dependent ATPase-like activity.

January 22, 2017

Monasterio O, Nova E, Diaz-Espinoza R.

 Biochem Biophys Res Commun. 2017 Jan 22;482(4):1194-1200. doi: 10.1016/j.bbrc.2016.12.011.