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Laboratorio de Biología Estructural y Molecular (BEM)

Centro de Equipamiento Mayor (CEM)

Facultad de Ciencias

Universidad de Chile

Las Palmeras 3425

Ñuñoa, Santiago

Chile

cem@uchile.cl

+56 2 29787380

Visitors:

Recent Publications

March 10, 2017

Monasterio O, Nova E, Diaz-Espinoza R. Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides. Arch Biochem Biophys. 2017 Mar 10. pii: S0003-9861(16)30535-5. doi: 10.1016/j.abb.2017.03.003.

January 22, 2017

Monasterio O, Nova E, Diaz-Espinoza R. Development of a novel catalytic amyloid displaying a metal-dependent ATPase-like activity. Biochem Biophys Res Commun. 2017 Jan 22;482(4):1194-1200. doi: 10.1016/j.bbrc.2016.12.011.

June 3, 2016

Marcoleta AE, Berríos-Pastén C, Nuñez G, Monasterio O, Lagos R. Klebsiella pneumoniae Asparagine tDNAs Are Integration Hotspots for Different Genomic Islands Encoding Microcin E492 Production Determinants and Other Putative Virulence Factors Present in Hypervirulent Strains. Front Microbiol. 2016 Jun 3;7:849. doi: 10.3389/fmicb.2016.00849.

January 28, 2016

Aguilera P, Marcoleta A, Lobos-Ruiz P, Arranz R, Valpuesta JM, Monasterio O, Lagos R. Identification of Key Amino Acid Residues Modulating Intracellular and In vitro Microcin E492 Amyloid Formation. Front Microbiol. 2016 Jan 28;7:35. doi: 10.3389/fmicb.2016.00035.

October 23, 2015

Gutierrez E, Benites J, Valderrama JA, Calderon PB, Verrax J, Nova E, Villanelo F, Maturana D, Escobar C, Lagos R, Monasterio O. Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly. Biochem Biophys Res Commun. 2015 Oct 23;466(3):418-25. doi: 10.1016/j.bbrc.2015.09.041.

August 4, 2014

den Blaauwen T, Andreu JM, Monasterio O. Bacterial cell division proteins as antibiotic targets. Bioorg Chem. 2014 Aug;55:27-38. doi: 10.1016/j.bioorg.2014.03.007.

July 25, 2014

Montecinos-Franjola F, James NG, Concha-Marambio L, Brunet JE, Lagos R, Monasterio O, Jameson DM. Single tryptophan mutants of FtsZ: nucleotide binding/exchange and conformational transitions. Biochim Biophys Acta. 2014 Jul;1844(7):1193-200. doi: 10.1016/j.bbapap.2014.03.012.

September 25, 2013

Marcoleta A, Marín M, Mercado G, Valpuesta JM, Monasterio O, Lagos R. Microcin e492 amyloid formation is retarded by posttranslational modification. J Bacteriol. 2013 Sep;195(17):3995-4004. doi: 10.1128/JB.00564-13.

May 9, 2013

Marcoleta A, Gutiérrez-Cortez S, Maturana D, Monasterio O, Lagos R. Whole-Genome Sequence of the Microcin E492-Producing Strain Klebsiella pneumoniae RYC492. Genome Announc. 2013 May 9;1(3). pii: e00178-13. doi: 10.1128/genomeA.00178-13.

February 13, 2013

Shin JY, Vollmer W, Lagos R, Monasterio O. Glutamate 83 and arginine 85 of helix H3 bend are key residues for FtsZ polymerization, GTPase activity and cellular viability of Escherichia coli: lateral mutations affect FtsZ polymerization and E. coli viability. BMC Microbiol. 2013 Feb 5;13:26. doi: 10.1186/1471-2180-13-26.