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Monasterio O. publications (last 10 years).

M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation


Reyes, JS, Fuentes-Lemus, E, Aspee, A, Davies, MJ, Monasterio, O, Lopez-Alarcon, C. FREE RADICAL BIOLOGY AND MEDICINE.

A tribute to Dr. Serge N. Timasheff, our mentor


Aune K., Lee J., Prakash V., Bhat R., Andreu J., Monasterio O., Perez-Ramirez B., Shearwin K., Arakawa T., Carpenter J., Crowe J., Crowe L., Somero G., Gagnon P., Charles M.T. Biophysical Reviews.

Functional characterization of the ATPase-like activity displayed by a catalytic amyloid


Castillo-Caceres C., Duran-Meza E., Nova E., Araya-Secchi R., Monasterio O., Diaz-Espinoza R. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.

Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides



Inhibition of Escherichia coli and Bacillus subtilis FtsZ Polymerization and Bacillus subtilis Growth by Dihydroxynaphtyl Aryl Ketones



The Ferric uptake regulator (Fur) and iron availability control the production and maturation of the antibacterial peptide microcin E492.


Marcoleta, AE, Gutiérrez-Cortez, S., Hurtado, F., Argandoña, Y., Corsini, G., Monasterio, O., and Lagos, R. PLoS one.

Evaluating different virulence traits of Klebsiella pneumoniae using the social amoeba Dictyostelium discoideum and zebrafish larvae as host models.

March, 2018

Marcoleta, AE, Varas, M.A, Ortiz-Severín, J. Vásquez, L., Berríos-Pastén,  C.,  Sabag, A., Chávez,  F.P., Allende, M.L., Santiviago, C.,  Monasterio, O.,  and Lagos, R.
Frontiers in Cellular and Infection Microbiology 8:30. doi: 10.3389/fcimb.2018.00030.

The chaperonin CCT promotes the formation of fibrillar aggregates of γ-tubulin.

January, 2018

Marcoleta, AE, Varas, M.A, Ortiz-Severín, J. Vásquez, L., Berríos-Pastén,  C.,  Sabag, A., Chávez,  F.P., Allende, M.L., Santiviago, C.,  Monasterio, O.,  and Lagos, R.
Biochim Biophys Acta. 2018 Apr;1866(4):519-526. doi: 10.1016/j.bbapap.2018.01.007.

Thermal adaptation of mesophilic and thermophilic FtsZ assembly by modulation of the critical concentration.

October, 2017

Concha-Marambio L, Maldonado P, Lagos R, Monasterio O, Montecinos-Franjola F.
PLoS One. 2017 Oct 5;12(10):e0185707. doi: 10.1371/journal.pone.0185707.

The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function.

July, 2017

Escobar-Álvarez E, Leinisch F, Araya G, Monasterio O, Lorentzen LG, Silva E, Davies MJ, López-Alarcón C.
Free Radic Biol Med. 112:60-68. doi: 10.1016/j.freeradbiomed.2017.07.014.

Bacterial Tubulins A and B Exhibit Polarized Growth, Mixed-Polarity Bundling, and Destabilization by GTP Hydrolysis.

October, 2017

Díaz-Celis C, Risca VI, Hurtado F, Polka JK, Hansen SD, Maturana D, Lagos R, Mullins RD, Monasterio O.
J Bacteriol. 2017 Sep 5;199(19). pii: e00211-17. doi: 10.1128/JB.00211-17.

Mutations on FtsZ lateral helix H3 that disrupt cell viability hamper reorganization of polymers on lipid surfaces.

June 20, 2017

Marquez, I.F.,  Mateos-Gil, P.,  Shin, J-Y., Lagos, R.,  Monasterio, O.,  Velez, M.
Biochim Biophys Acta  – Biomembranes. 1859, 1815-1827.

Overcoming electrostatic repulsions during amyloid assembly: effect of pH and interaction with divalent metals using model peptides.

March 10, 2017

Diaz-Espinoza R, Nova E, Monasterio O.

Arch Biochem Biophys. 2017 Mar 10;621:46-53. doi: 10.1016/

Development of a novel catalytic amyloid displaying a metal-dependent ATPase-like activity.

January 22, 2017

Monasterio O, Nova E, Diaz-Espinoza R.

 Biochem Biophys Res Commun. 2017 Jan 22;482(4):1194-1200. doi: 10.1016/j.bbrc.2016.12.011.

Inhibition of the hantavirus fusion process by predicted domain III and stem peptides from glycoprotein GC.

July 14, 2016

Barriga GP, Villalón-Letelier F, Márquez CL, Bignon EA, Acuña R, Ross BH, Monasterio O, Mardones GA, Vidal SE, Tischler ND.
PLoS Negl Trop Dis. 2016 Jul 14;10(7):e0004799. doi: 10.1371/journal.pntd.0004799.

Identification of key amino acid residues modulating intracellular and in vitro microcin E492 amyloid formation.

January 28, 2016

Aguilera P, Marcoleta A, Lobos-Ruiz P, Arranz R, Valpuesta JM, Monasterio O, Lagos R.
Front Microbiol. 2016 Jan 28;7:35. doi: 10.3389/fmicb.2016.00035

Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly.

October 23, 2015

Gutierrez E, Benites J, Valderrama JA, Calderon PB, Verrax J, Nova E, Villanelo F, Maturana D, Escobar C, Lagos R, Monasterio O.
Biochem Biophys Res Commun. 2015 Oct 23;466(3):418-25. doi: 10.1016/j.bbrc.2015.09.041.

Bacterial cell division proteins as antibiotic targets.

August, 2014

den Blaauwen T, Andreu JM, Monasterio O.

Bioorg Chem. 2014 Aug;55:27-38. doi: 10.1016/j.bioorg.2014.03.007. Epub 2014 Apr 4.

Single tryptophan mutants of FtsZ: nucleotide binding/exchange and conformational transitions.

July, 2014

Montecinos-Franjola F, James NG, Concha-Marambio L, Brunet JE, Lagos R, Monasterio O, Jameson DM.
Biochim Biophys Acta. 2014 Jul;1844(7):1193-200. doi:10.1016/j.bbapap.2014.03.012.

Microcin E492 amyloid formation is retarded by posttranslational modification.

July 8, 2013

Marcoleta A, Marín M, Mercado G, Valpuesta JM, Monasterio O, Lagos R.
J Bacteriol. 2013 Sep;195(17):3995-4004. doi: 10.1128/JB.00564-13

Whole-genome sequence of the microcin E492-producing strain Klebsiella pneumoniae RYC492.

May 9, 2013

Marcoleta A, Gutiérrez-Cortez S, Maturana D, Monasterio O, Lagos R.
Genome Announc. 2013 May 9;1(3). pii: e00178-13. doi: 10.1128/genomeA.00178-13

Glutamate 83 and arginine 85 of helix H3 bend are key residues for FtsZ polymerization, GTPase activity and cellular viability of Escherichia coli: lateral mutations affect FtsZ polymerization and E. coli viability.

February 5, 2013

Shin JY, Vollmer W, Lagos R, Monasterio O.
BMC Microbiol. 2013 Feb 5;13:26. doi: 10.1186/1471-2180-13-26.

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